Educational reference only — not medical advice. This calculator does maths only and does not recommend any dose. Always confirm your dose and preparation with a licensed healthcare provider or pharmacist.
Reconstitution Calculator
Results update live as you type. Your dose must come from your prescription or provider — this tool never suggests one.
Printed on the vial label — the total powder in the vial.
The volume of bacteriostatic water you mix into the vial.
Enter the dose exactly as given to you. 1 mg = 1,000 mcg.
U-100 syringes: 100 units = 1 mL, whatever the barrel size.
Nothing you type leaves this page — the calculation runs entirely in your browser. Educational reference only, not medical advice.
Sermorelin has the most complicated backstory of any peptide on this site: it used to be an approved medicine, then it wasn’t, and today it exists in a grey zone between compounding pharmacies and research suppliers. The maths, thankfully, is simple — and the first thing to know is that your pharmacy’s instructions always beat this calculator.
What is Sermorelin?
Sermorelin is a synthetic version of the first 29 amino acids of GHRH (growth hormone-releasing hormone). It acts on the pituitary GHRH receptor to stimulate growth hormone release, rather than supplying growth hormone itself. Its former brand name was Geref.
Its regulatory history needs stating precisely. The FDA approved Geref in 1990 (a diagnostic ampoule) and 1997 (treatment vials) for paediatric growth hormone deficiency and growth-hormone testing. The manufacturer discontinued the branded product in 2008, and the FDA withdrew both approvals in 2009. In 2013 the FDA determined Geref was not withdrawn for reasons of safety or effectiveness — it was a commercial/manufacturing decision. There is no currently marketed FDA-approved sermorelin product. Today it is available in the US only through compounding pharmacies with a valid prescription (it remains in the FDA 503A Category 1 list as of June 2026), and compounded medications are themselves not FDA-approved drug products. It is prescription-only, not a controlled substance, and WADA prohibits it for tested athletes.
The vial maths.
Vial sizes differ by channel, which is why the calculator offers more options here than elsewhere: the compounded set is 3, 6, 9 and 15 mg; the research set is 2, 5, 9, 10 and 15 mg. Use the size printed on your own vial.
Worked example — 5 mg vial, 2 mL of BAC water, example dose 250 mcg:
- Concentration: (5 × 1,000) ÷ 2 = 2,500 mcg/mL
- Each unit holds 2,500 ÷ 100 = 25 mcg
- Units for the example dose: 250 ÷ 25 = 10 units (0.1 mL)
- Doses in the vial: 5,000 ÷ 250 = 20 doses
Sermorelin doses are discussed in micrograms (sources list a 200–300 mcg range in their reference tables), even though the vials are labelled in milligrams — so the mg → mcg conversion is doing real work on this page. A 3 mg compounded vial in 3 mL gives 1,000 mcg/mL, where 0.10 mL (10 units) is 100 mcg.
If your sermorelin came from a compounding pharmacy, its own label and your prescriber’s instructions take priority — use this calculator only as an independent cross-check of the arithmetic. If the two disagree, stop and ask the pharmacy before drawing anything.
Storage (commonly cited):
Unmixed vial refrigerated at 2–8 °C (stable up to 24 months per one source) or frozen at −20 °C for long-term storage. Once mixed, refrigerate at 2–8 °C, protect from light, do not freeze. Usable window varies by source — 14–28 days, 28 days most commonly cited, 30 days, 10–14 days, 4–6 weeks, and 90 days as a pharmacy-assigned beyond-use date (pharmacy-specific, not a research-vial figure). Do not treat any single figure as settled.
FAQs
How do I calculate syringe units for sermorelin?
Exactly like any other peptide: a 5 mg vial in 2 mL gives 2,500 mcg/mL, so each unit holds 25 mcg and your units = your dose in mcg ÷ 25. Enter your vial size, water and prescribed dose in the calculator above.
How many doses are in a sermorelin vial?
Total mcg in the vial ÷ your dose in mcg. A 5 mg vial is 5,000 mcg, so at an example dose of 250 mcg it holds 20 doses.
My pharmacy gave me instructions with the vial. Should I follow those or this calculator?
Your pharmacy’s instructions and your prescriber’s directions always win — they know your prescription. Use this page only to double-check the arithmetic. If the two disagree, stop and ask the pharmacy before drawing anything.
Is sermorelin FDA-approved?
Not currently. It was approved as Geref (1990/1997) and discontinued in 2008 for commercial reasons, not safety or effectiveness. There is no currently marketed FDA-approved product; it is available only via compounding pharmacy with a prescription.
Related calculators
See also the CJC-1295 Calculator, the Ipamorelin Calculator and the Peptide Calculator home page.
Educational reference only — not medical advice. This calculator does maths only and does not recommend any dose. Always confirm your dose and preparation with a licensed healthcare provider or pharmacist.