Educational reference only — not medical advice. This calculator does maths only and does not recommend any dose. Always confirm your dose and preparation with a licensed healthcare provider or pharmacist.
Reconstitution Calculator
Results update live as you type. Your dose must come from your prescription or provider — this tool never suggests one.
Printed on the vial label — the total powder in the vial.
The volume of bacteriostatic water you mix into the vial.
Enter the dose exactly as given to you. 1 mg = 1,000 mcg.
U-100 syringes: 100 units = 1 mL, whatever the barrel size.
Nothing you type leaves this page — the calculation runs entirely in your browser. Educational reference only, not medical advice.
MOTS-C is the odd one out in this collection for a practical reason: its numbers are bigger. The vials are larger, and the amounts people discuss are in milligrams, not micrograms. If you are used to other peptides’ mcg-scale maths, that shift is exactly where mistakes happen — so this page is built around it.
What is MOTS-C?
MOTS-C is a 16-amino-acid peptide with an unusual origin: its instructions are encoded in the mitochondrial genome — the small set of DNA inside mitochondria — rather than in the cell nucleus. Its full name is Mitochondrial Open Reading Frame of the 12S rRNA-c. It was first described in 2015 by researchers at the University of Southern California and is studied in laboratory research into metabolism and exercise response. It is sold as a freeze-dried powder. No published human randomised controlled trials of administered MOTS-C were reported by the sources checked.
It is not approved by the FDA for any use and is sold as a research chemical. It is not a controlled substance.
The vial maths — and the mg difference.
MOTS-C vials are most commonly sold as 5 mg and 10 mg, with 20 mg and 40 mg also sold (30 mg appears on only one source’s list). Because the vials are bigger, amounts are commonly discussed in milligrams rather than micrograms — which makes the mg/mcg conversion on this page especially important. A 1 mg amount is 1,000 mcg; mixing the two up is a 1,000-fold error.
Worked example — 10 mg vial, 2 mL of BAC water, example amount 1 mg:
- First convert the amount: 1 mg = 1,000 mcg
- Concentration: (10 × 1,000) ÷ 2 = 5,000 mcg/mL
- Each unit holds 5,000 ÷ 100 = 50 mcg
- Units for the example amount: 1,000 ÷ 50 = 20 units (0.2 mL)
- Amounts in the vial: 10,000 ÷ 1,000 = 10 amounts
Use the mg toggle on the calculator rather than converting in your head — it applies the ×1,000 for you, and it removes the most common source of error on this page.
Storage (commonly cited):
Unmixed vial refrigerated at 2–8 °C, or frozen at −20 °C for long-term storage, sealed and protected from light. Once mixed, refrigerate at 2–8 °C and do not freeze the solution. How long a mixed vial is said to keep varies widely — 28 days is the most commonly cited figure, but sources range from about 7 days to 4–6 weeks. Do not treat any single window as settled; your product’s own label takes precedence.
FAQs
What concentration is a 10 mg MOTS-C vial in 2 mL?
10 × 1,000 ÷ 2 = 5,000 mcg/mL. Each U-100 unit contains 50 mcg, so your units = your amount in mcg ÷ 50. An amount of 1 mg (1,000 mcg) at this mix is 20 units.
My MOTS-C amount is in mg. How do I use the calculator?
Use the mg toggle next to the dose field, or convert by hand: mg × 1,000 = mcg. Then units = amount in mcg ÷ concentration in mcg/mL × 100. Mixing up mg and mcg is a 1,000× error, so double-check which unit your amount is written in.
How many amounts are in a 10 mg MOTS-C vial?
10,000 mcg ÷ your amount in mcg. At an example amount of 1,000 mcg (1 mg) that is 10 amounts.
Why are MOTS-C vials bigger than most peptides’?
Because the amounts discussed for MOTS-C are in the milligram range rather than the microgram range, so the vials hold more powder. The maths is identical — only the scale changes.
Related calculators
See also the GHK-Cu Calculator and the Peptide Calculator home page.
Educational reference only — not medical advice. This calculator does maths only and does not recommend any dose. Always confirm your dose and preparation with a licensed healthcare provider or pharmacist.